Blar i forfatter "Boutron-Ruault, Marie-Christine"

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    • Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study 

      Llaha, Fjorida; Cayssials, Valerie; Farràs, Marta; Agudo, Antonio; Sandström, Maria; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Laouali, Nasser; Truong, Thérèse; Le Cornet, Charlotte; Katzke, Verena; Schulze, Matthias; Palli, Domenico; Krogh, Vittorio; Signoriello, Simona; Tumino, Rosario; Ricceri, Fulvio; Skeie, Guri; Jensen, Torill Miriam Enget; Chen, Sairah Lai Fa; Lasheras, Cristina; Rodriguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Guevara, Marcela; Almquist, Martin; Nilson, Lena Maria; Hennings, Joakim; Papier, Keren; Heath, Alicia; Weiderpass, Elisabete; Rinaldi, Sabina; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-02)
      Background: The Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods: ...

    • Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study 

      Dossus, Laure; Franceschi, Silvia; Biessy, Carine; Navionis, Anne-Sophie; Travis, Ruth C.; Weiderpass, Elisabete; Scalbert, Augustin; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Bonnet, Fabrice; Fournier, Agnès; Fortner, Renée Turzanski; Kaaks, Rudolf; Aleksandrova, Krasimira; Trichopoulou, Antonia; La Vecchia, Carlo; Peppa, Eleni; Tumino, Rosario; Panico, Salavatore; Palli, Domenico; Agnoli, Claudia; Vineis, Paolo; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Skeie, Guri; Zamora-Ros, Raul; Chirlaque, María-Dolores; Ardanaz, Eva; Sánchez, Maria-Jose; Quirós, Jose Ramón; Dorronsoro, Miren; Sandström, Maria; Nilsson, Lena Maria; Schmidt, Julie A.; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Aune, Dagfinn; Riboli, Elio; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
      Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...

    • Adult weight change and premenopausal breast cancer risk: A prospective pooled analysis of data from 628,463 women 

      Schoemaker, Minouk J.; Nichols, Hazel B.; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; O'Brien, Katie M.; Adami, Hans Olov; Baglietto, Laura; Bernstein, Leslie; Bertrand, Kimberly A.; Boutron-Ruault, Marie-Christine; Chen, Yu; Connor, Avonne E.; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G; Gram, Inger Torhild; Hankinson, Susan E.; Kaaks, Rudolf; Key, Timothy J.; Kirsh, Victoria A.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Ma, Huiyan; Milne, Roger L.; Ozasa, Kotaro; Palmer, Julie R.; Riboli, Elio; Rohan, Thomas E.; Sacerdote, Carlotta; Sadakane, Atsuko; Sund, Malin; Tamimi, Rulla M.; Trichopoulou, Antonia; Ursin, Giske; Visvanathan, Kala; Weiderpass, Elisabete; Willett, Walter C.; Wolk, Alicja; Zeleniuch-Jacquotte, Anne; Sandler, Dale P.; Swerdlow, Anthony J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-03)
      Early‐adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual‐level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk ...

    • Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Sanikini, Harinakshi; Muller, David C.; Sophiea, Marisa; Rinaldi, Sabina; Agudo, Antonio; Duell, Eric J.; Weiderpass, Elisabete; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Cervenka, Iris; Boeing, Heiner; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Pala, Valeria; Palli, Domenico; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Rylander, Charlotta; López, María-Dolores Chirlaque; Sánchez, Maria-Jose; Ardanaz, Eva; Regnér, Sara; Stocks, Tanja; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Aune, Dagfinn; Tong, Tammy Y.N.; Kliemann, Nathalie; Murphy, Neil; Chadeau-Hyam, Marc; Gunter, Mark J.; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-03)
      Obesity has been associated with upper gastrointestinal cancers; however, there are limited prospective data on associations by subtype/subsite. Obesity can impact hormonal factors, which have been hypothesized to play a role in these cancers. We investigated anthropometric and reproductive factors in relation to esophageal and gastric cancer by subtype and subsite for 476,160 participants from the ...

    • The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC) 

      Sawada, Norie; Wark, Petra A.; Merritt, Melissa A.; Tsugane, Shoichiro; Ward, Heather A.; Rinaldi, Sabina; Weiderpass, Elisabete; Dartois, Laureen; His, Mathilde; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renée; Kaaks, Rudolf; Overvad, Kim; Redondo, María-Luisa; Travier, Noemie; Molina-Portillo, Elena; Dorronsoro, Miren; Cirera, Lluis; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Valanou, Elissavet; Masala, Giovanna; Pala, Valeria; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Melander, Olle; Manjer, Jonas; da Silva, Marisa Eleonor; Skeie, Guri; Tjønneland, Anne; Olsen, Anja; Gunter, Mark J.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-03)
      Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly ...

    • Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study 

      Baumeister, Sebastian E.; Schlesinger, Sabrina; Aleksandrova, Krasimira; Jochem, Carmen; Jenab, Mazda; Gunter, Marc J.; Overvad, Kim; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Fournier, Agnès; Kühn, Tilman; Kaaks, Rudolf; Pischon, Tobias; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; La Vecchia, Carlo; Masala, Giovanna; Panico, Salvatore; Fasanelli, Francesca; Tumino, Rosario; Grioni, Sara; Bueno-de-Mesquita, Hendrik Bastiaan; Vermeulen, Roel; May, Anne M.; Borch, Kristin Benjaminsen; Oyeyemi, Sunday Oluwafemi; Ardanaz, Eva; Rodríguez-Barranco, Miguel; Chirlaque López, María Dolores; Felez-Nobrega, Mireia; Sonestedt, Emily; Ohlsson, Bodil; Hemmingsson, Oskar; Werner, Mårten; Perez-Cornago, Aurora; Ferrari, Pietro; Stepien, Magdalena; Freisling, Heinz; Tsilidis, Konstantinos K.; Ward, Heather; Riboli, Elio; Weiderpass, Elisabete; Leitzmann, Michael F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-22)
      <i>Background & Aims</i> - To date, evidence on the association between physical activity and risk of hepatobiliary cancers has been inconclusive. We examined this association in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC).<p><p> <i>Methods</i> - We identified 275 hepatocellular carcinoma (HCC) cases, 93 intrahepatic bile duct cancers (IHBCs), and 164 non-gallbladder ...

    • Association between soft drink consumption and mortality in 10 European countries 

      Mullee, Amy; Romaguera, Dora; Pearson-Stuttard, Jonathan; Viallon, Vivian; Stepien, Magdalena; Freisling, Heinz; Fagherazzi, Guy; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Tjønneland, Anne; Halkjær, Jytte; Overvad, Kim; Weiderpass, Elisabete; Skeie, Guri; Parr, Christine Louise; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Tong, Tammy Y.N.; Schmidt, Julie A.; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Verschuren, W.M. Monique; Boer, Jolanda M.A.; Vermeulen, Roel; Ramne, Stina; Sonestedt, Emily; Van Guelpen, Bethany; Holgersson, Pernilla Lif; Tsilidis, Konstantinos K.; Heath, Alicia K.; Muller, David; Riboli, Elio; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p> <i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p> <i>Design, ...

    • Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort 

      Butt, Julia; Jenab, Mazda; Werner, Jill; Fedirko, Veronika; Weiderpass, Elisabete; Dahm, Christina C.; Tjønneland, Anne; Olsen, Anja; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Turzanski-Fortner, Renée; Aleksandrova, Krasimira; Schulze, Matthias B.; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosaria; Sacerdote, Carlotta; Bueno-De-Mesquita, Bas; van Gils, Carla H.; Gram, Inger Torhild; Lukic, Marko; Sala, Núria; Sánchez Pérez, Maria José; Ardanaz, Eva; Chirlaque, Maria-Dolores; Palmquist, Richard; Löwenmark, Thyra; Travis, Ruth C.; Heath, Alicia K.; Cross, Amanda J.; Freisling, Heinz; Zouiouich, Semi; Aglago, Elom; Waterboer, Tim; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-20)
      Experimental evidence has implicated genotoxic <i>Escherichia coli (E. coli)</i> and enterotoxigenic <i>Bacteroides fragilis</i> (ETBF) in the development of colorectal cancer (CRC). However, evidence from epidemiological studies is sparse. We therefore assessed the association of serological markers of <i>E. coli</i> and ETBF exposure with odds of developing CRC in the European Prospective Investigation ...

    • Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status 

      Fedirko, Veronika; Jenab, Mazda; Méplan, Catherine; Jones, Jeb S.; Zhu, Wanzhe; Schomburg, Lutz; Siddiq, Afshan; Hybsier, Sandra; Overvad, Kim; Tjønneland, Anne; Omichessan, Hanane; Perduca, Vittorio; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Aleksandrova, Krasimira; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Agnoli, Claudia; Naccarati, Alessio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Weiderpass, Elisabete; Skeie, Guri; Nøst, Therese Haugdahl; Lujan-Barroso, Leila; Quirós, Jose Ramón; Huerta, José María; Rodríguez-Barranco, Miguel; Barricarte, Aurelio; Gylling, Björn; Harlid, Sophia; Bradbury, Kathryn Erica; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Murphy, Neil; Freisling, Heinz; Tsilidis, Kostas; Aune, Dagfinn; Riboli, Elio; Hesketh, John E.; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-25)
      Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein and Se metabolic pathway genes. <i>Illumina Goldengate</i> assays were designed and resulted in the genotyping of 1040 variants in 154 genes ...

    • Associations between dietary inflammatory scores and biomarkers of inflammation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Viallon, Vivian; Artaud, Fanny; Hébert, James R.; Shivappa, Nitin; Agudo, Antonio; Tjønneland, Anne; Mellemkjær, Lene; Kaaks, Rudolf; Katzke, Verena A.; Schulze, Matthias B.; Frenoy, Pauline; Mancini, Francesca Romana; De Magistris, Maria Santucci; Macciotta, Alessandra; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Chirlaque, María-Dolores; Petrova, Dafina; Castro-Espin, Carlota; Quirós, J. Ramón; Guevara, Marcela; Amiano, Pilar; Borné, Yan; Sandström, Maria; Nilsson, Lena Maria; Heath, Alicia K.; Mayen, Ana-Lucia; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Dossus, Laure; Rinaldi, Sabina; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-17)
      Background - Since the first version of the dietary inflammatory index (DII®) developed in the past decade, several other versions have been developed. However, to date no study has attempted to compare these versions with respect to their associations with biomarkers of inflammation.<p> <p>Objective - We aimed to investigate the relationship between four dietary inflammatory scores [DII, two ...

    • Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study 

      Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, Mariá-José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay-Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...

    • Baseline and lifetime alcohol consumption and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Al-Rahmoun, Marie; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Lukic, Marko; Sánchez, Maria J.; Pala, Valeria; Tumino, Rosario; Chiodini, Paolo; Amiano, Pilar; Colorado-Yohar, Sandra; Chirlaque, María-Dolores; Ardanaz, Eva; Bonet, Catalina; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Overvad, Kim; Dahm, Christina C.; Antoniussen, Christian S.; Tjønneland, Anne; Kyrø, Cecilie; Bueno-de-Mesquita, Bas; Manjer, Jonas; Jansson, Malin; Esberg, Anders; Mori, Nagisa; Ferrari, Pietro; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Experimental evidence suggests that alcohol induces cutaneous carcinogenesis, yet epidemiological studies on the link between alcohol intake and skin cancer have been inconsistent. The European Prospective Investigation into Cancer and Nutrition (EPIC) is a prospective cohort initiated in 1992 in 10 European countries. Alcohol intake at baseline and average lifetime alcohol intake were assessed using ...

    • Biomarkers of folate and vitamin B12 and breast cancer risk: report from the EPIC cohort 

      Matejcic, Marco; De Batlle, Jordi; Ricci, Cristian; Biessy, Carine; Perrier, Flavie; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Cadeau, Claire; His, Mathilde; Cox, David G.; Boeing, Heiner; Fortner, Renée Turzanski; Kaaks, Rudolf; Lagiou, Pagona; Trichopoulou, Antonia; Benetou, Vassiliki; Tumino, Rosario; Panico, Salvatore; Sieri, Sabina; Palli, Domenico; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Skeie, Guri; Amiano, Pilar; Sánchez, María-José; Chirlaque, María-Dolores; Barricarte, Aurelio; Quirós, José Ramón; Buckland, Genevieve; van Gils, Carla H.; Peeters, Petra H.; Key, Timothy J.; Riboli, Elio; Gylling, Björn; Zeleniuch-Jacquotte, Anne; Gunter, Mark J.; Romieu, Isabelle; Chajès, Véronique (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-01)
      Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually ...

    • Breast cancer risk after recent childbirth: A pooled analysis of 15 prospective studies 

      Nichols, Hazel B.; Schoemaker, Minouk J.; Cai, Jianwen; Xu, Jiawei; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; Adami, Hans Olov; Baglietto, Laura; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Dorronsoro, Miren; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger Torhild; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Merritt, Melissa A.; Milne, Roger L.; Pala, Valeria; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Sund, Malin; Tamimi, Rulla M.; Tjønneland, Anne; Trichopoulou, Antonia; Ursin, Giske; Vatten, Lars Johan; Visvanathan, Kala; Weiderpass, Elisabete; Wolk, Alicja; Zheng, Wei; Weinberg, Clarice R.; Swerdlow, Anthony J.; Sandler, Dale P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Background</i>: Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or specific tumor subtype has rarely been evaluated.<p> <p><i>Objective</i>: To characterize breast cancer risk in relation to recent childbirth.<p> <p>Design</i> : Pooled ...

    • Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts 

      Rothwell, Joseph A.; Bešević, Jelena; Dimou, Niki; Breeur, Marie; Murphy, Neil; Jenab, Mazda; Wedekind, Roland; Viallon, Vivian; Ferrari, Pietro; Achaintre, David; Gicquiau, Audrey; Rinaldi, Sabina; Scalbert, Augustin; Huybrechts, Inge; Prehn, Cornelia; Adamski, Jerzy; Cross, Amanda J.; Keun, Hector; Chadeau-Hyam, Marc; Boutron-Ruault, Marie-Christine; Overvad, Kim; Dahm, Christina C.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Zamora-Ros, Raul; Tsilidis, Kostas K.; Eichelmann, Fabian; Schulze, Matthias B.; van Guelpen, Bethany; Vidman, Linda; Sánchez, Maria-José; Amiano, Pilar; Ardanaz, Eva; Smith-Byrne, Karl; Travis, Ruth; Katzke, Verena; Kaaks, Rudolf; Derksen, Jeroen W. G.; Colorado-Yohar, Sandra; Tumino, Rosario; Bueno-de-Mesquita, Bas; Vineis, Paolo; Palli, Domenico; Pasanisi, Fabrizio; Eriksen, Anne Kirstine; Tjønneland, Anne; Severi, Gianluca; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-28)
      Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk of colorectal cancer. We investigated circulat‑ ing levels of amino acids in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank ...

    • Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans 

      Stepien, Magdalena; Hughes, David J.; Hybsier, Sandra; Bamia, Christina; Tjønneland, Anne; Overvad, Kim; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Orfanos, Phlippos; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Lasheras, Cristina; Bonet Bonet, Catalina; Molina-Portillo, Elena; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Ohlsson, Bodil; Sjöberg, Klas; Werner, Mårten; Shungin, Dmitry; Wareham, Nick; Khaw, Kay-Tee; Travis, Ruth C.; Freisling, Heinz; Cross, Amanda J.; Schomburg, Lutz; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-02)
      Background:<br>Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.<br>Methods:<br>A nested ...

    • Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort 

      van Roekel, Eline H.; Trijsburg, Laura; Assi, Nada; Carayol, Marion; Achaintre, David; Murphy, Neil; Rinaldi, Sabina; Schmidt, Julie A.; Stepien, Magdalena; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salavatore; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Ardanaz, Eva; Lujan-Barroso, Leila; Quirós, José Ramón; Huerta, José María; Molina-Portillo, Elena; Dorronsoro, Miren; Tsilidis, Konstantinos K.; Riboli, Elio; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Håkansson, Anders; Malm, Johan; Weijenberg, Matty P.; Gunter, Marc J.; Jenab, Mazda; Johansson, Mattias; Travis, Ruth C.; Scalbert, Augustin; Ferrari, Pietro (Journal article; Peer reviewed, 2018-05-22)
      Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at ...

    • Circulating RANKL and RANKL/OPG and breast cancer risk by ER and PR subtype: Results from the EPIC cohort. 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Overvad, Kim; Holm, Marianne; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; His, Mathilde; Kvaskoff, Marina; Boeing, Heiner; Lagiou, Pagona; Papatesta, Eleni-Maria; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; van Gils, Carla H.; Peeters, Petra H.; Weiderpass, Elisabete; Agudo, Antonio; Sánchez, María-José; Chirlaque, Maria-Dolores; Ardanaz, Eva; Amiano, Pilar; Khaw, Kay Tee; Travis, Ruth; Dossus, Laure; Gunter, Mark; Rinaldi, Sabina; Merritt, Melissa; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-31)
      Receptor activator of nuclear factor-kappa B (RANK)-RANK ligand (RANKL) signaling promotes mammary tumor development in experimental models. Circulating concentrations of soluble RANKL (sRANKL) may influence breast cancer risk via activation of RANK signaling; this may be modulated by osteoprotegerin (OPG), the decoy receptor for RANKL. sRANKL and breast cancer risk by hormone receptor subtype has ...

    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...

    • Citrus intake and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Cervenka, Iris; Al-Rahmoun, Marie; Mancini, Francesca R.; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Trichopoulou, Antonia; Peppa, Eleni; La Vecchia, Carlo; Overvad, Kim; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Perez-Cornago, Aurora; Jakszyn, Paula; Grioni, Sara; Schulze, Matthias B.; Skeie, Guri; Lasheras, Christina; Colorado-Yohar, Sandra; RodrÍguez-Barranco, Miguel; Kühn, Tilman; Katzke, Verena A.; Amiano, Pilar; Tumino, Rosario; Panico, Salvatore; Ezponda, Ana; Sonestedt, Emily; Scalbert, Augustin; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-24)
      Citrus intake has been suggested to increase the risk of skin cancer. Although this relation is highly plausible biologically, epidemiologic evidence is lacking. We aimed to examine the potential association between citrus intake and skin cancer risk. EPIC is an ongoing multi-center prospective cohort initiated in 1992 and involving ~ 520,000 participants who have been followed-up in 23 centers from ...